Mitochondrial Dysfunction and Multiple Sclerosis
نویسندگان
چکیده
منابع مشابه
Relationship between Mitochondrial Dysfunction and Multiple Sclerosis: A Review Study
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system that inflammation, demyelination, oligodendrocyte loss, gliosis, axonal injury and neurodegeneration are the main histopathological hallmarks of the disease. Although MS was classically thought as a demyelinating disease, but axonal injury occurs commonly in acute inflammatory lesions. In MS mi...
متن کاملrelationship between mitochondrial dysfunction and multiple sclerosis: a review study
multiple sclerosis (ms) is a chronic inflammatory demyelinating disease of the central nervous system that inflammation, demyelination, oligodendrocyte loss, gliosis, axonal injury and neurodegeneration are the main histopathological hallmarks of the disease. although ms was classically thought as a demyelinating disease, but axonal injury occurs commonly in acute inflammatory lesions. in ms mi...
متن کاملMitochondrial dysfunction and neurodegeneration in multiple sclerosis
Multiple sclerosis (MS) has traditionally been considered an autoimmune inflammatory disorder leading to demyelination and clinical debilitation as evidenced by our current standard anti-inflammatory and immunosuppressive treatment regimens. While these approaches do control the frequency of clinical relapses, they do not prevent the progressive functional decline that plagues many people with ...
متن کاملRepeated Administration of Mercury Accelerates Progression of Multiple Sclerosis through Mitochondrial Dysfunction
Multiple Sclerosis (MS) is a neurodegenerative and autoimmune disease that it’s molecular etiology and factors involving in its progression remains unknown. In this study for evaluation effect of mercuric on progression of MS we investigated the additive effect of mercuric sulfide on the brain mitochondrial dysfunction in experimental autoimmune encephalomyelitis (EAE) model of MS in C57BL/6 mi...
متن کاملRepeated Administration of Mercury Accelerates Progression of Multiple Sclerosis through Mitochondrial Dysfunction
Multiple Sclerosis (MS) is a neurodegenerative and autoimmune disease that it’s molecular etiology and factors involving in its progression remains unknown. In this study for evaluation effect of mercuric on progression of MS we investigated the additive effect of mercuric sulfide on the brain mitochondrial dysfunction in experimental autoimmune encephalomyelitis (EAE) model of MS in C57BL/6 mi...
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ژورنال
عنوان ژورنال: Biology
سال: 2019
ISSN: 2079-7737
DOI: 10.3390/biology8020037